Unlock Trophies
Savior of the Universe (Platinum) - You got them all.
Extermination (Bronze) - Kill 50 aliens.
Annihilation (Bronze) - Kill 100 aliens.
Nuclear Devastation (Bronze) - Kill 250 aliens.
On the Noggin' (Bronze) - Kill 30 aliens with headshots.
Hippy-Stomper (Bronze) - Foot stomp 12 aliens.
Judge, Jury, Executioner (Bronze) - Execute 20 aliens.
Trapper (Bronze) - Kill 10 aliens with Trip Mines.
Freeze Well! (Bronze) - Kill 15 frozen aliens.
Road Rage (Bronze) - Kill 15 aliens with the monster truck.
Call Waiting (Silver) - Listen to all phone messages.
Bucket Head (Bronze) - Find all 3 helmets in the SP campaign.
Party Animal (Bronze) - Drink all of the beers in the strip club.
Pescaphobe (Bronze) - Kill all of the catfish in the underwater level.
Drawrings (Bronze) - Doodle something on the whiteboard in SP.
I Need a Date (Bronze) - Look at every page of a calender in SP.
Sticky Bomb Like You! (Bronze) - Put a Trip Mine on a live alien.
Big Guns, Big Ships (Bronze) - Blow up 5 enemy Gunships or Dropships.
Air-Duke (Silver) - Win air hockey with a score of 7-0 in the strip club.
Balls of Steel (Silver) - Earn a 1,000,000 pinball score in SP.
Fork the Pork (Bronze) - Kill 6 aliens with the forklift.
Dead Useful (Bronze) - Kill 10 aliens with environmental explosives.
Tosser...in the Literal Sense (Bronze) - Kill 10 aliens with tossed objects.
Duke Angry, Duke SmasH! (Bronze) - Kill 15 aliens with melee attacks while on steroids.
Noms (Bronze) - Eat 10 pieces of food in SP.
Natural Disaster 3x (Bronze) - Kill 3 aliens at once.
Full Body Tourettes (Bronze) - Get knocked down 10 times.
Turd Burglar (Bronze) - Find and steal a piece of poo.
I Need a Towel (Bronze) - Get hit by 10 Pregnator bombs.
Baron von Nukem (Bronze) - Shoot down 20 alien fighters.
Lots of Whacking (Bronze) - Win a game of Alien Abortion in the strip club.
Companion Barrel (Bronze) - Unlock the secret closet at the end of the Forkstop.
One-Eyed Freak (Bronze) - Defeat the Cycloid.
Pit Champion (Bronze) - Defeat the Battlelord in Las Vegas.
Not Bad for a Human (Silver) - Defeat the Alien Queen.
A Good Dam Fight (Silver) - Defeat the Battlelord on the Hoover Dam.
Flagon of Chuckles (Bronze) - Drink a beer in SP.
Juiced (Bronze) - Take steroids in SP.
He's Got a Hologram! (Bronze) - Use a Holoduke in SP.
Substance Abuser (Bronze) - Drink beer while on steroids or vice-versa in SP.
I Am All That Is Man (Silver) - Discover all ego cap rewards.
Gunslinger (Silver) - Carry the gold pistol through the whole SP campaign.
Sunday, Black Sunday (Bronze) - Shoot down the blimp above the stadium.
Nobody Likes a Whiner (Bronze) - Knock out the talent at the talk show.
Octacide (Silver) - Defeat the Octaking.
Beating the One-Eyed Worm (Silver) - Defeat the Leech.
Piece of Cake (Bronze) - Complete the SP campaign on Easy Difficulty.
Let's Rock (Silver) - Complete the SP campaign on Normal Difficulty.
Come Get Some (Gold) - Complete the SP campaign on Hard Difficulty.
Damn, I'm Good (Gold) - Complete the SP campaign on Insane Difficulty.
Special Thanks (Bronze) - Watch the credits all the way through.
Additionally, there are twelve The Doctor Who Cloned Me DLC trophies:
Another Piece of Cake (Bronze) - Beat The Doctor Who Cloned me on Easy Difficulty.
Heart to Heart (Bronze) - Finish Doctor Proton.
Hedonist, not Misogynist (Bronze) - Discover and reject the video game that lets you slap women.
I Am All That Is Man - Again! (Bronze) - Discover all Ego cap rewards in The Doctor Who Cloned Me.
Bloody Red Rover (Bronze) - Kill 30 enemies with the moon rover.
Come Get A Little More (Bronze) - Beat The Doctor Who Cloned me on Hard Difficulty.
Damn, I'm REALLY Good (Bronze) - Beat The Doctor Who Cloned me on Insane Difficulty.
Scientits (Bronze) - Earn a 1,000,000 pinball score on the Scientits pinball machine.
Threesome (Bronze) - Kill 3 enemies within 3 seconds with the Impregnader.
Let's Rock Out (Bronze) - Beat The Doctor Who Cloned me on Normal Difficulty.
Passive Aggressive (Bronze) - Let 20 enemies die by someone else's hand.
Bubble Buster (Bronze) - Kill 10 expanded enemies with melee attacks.
Unlock Bonus Options
Successfully complete the game under the indicated difficulty setting to unlock the following options at the "Extras" menu, usable in single player mode. Note: Enabling the "cheat" options will prevent Ego points and achievements/trophies from being earned.
Concept Arts - Normal difficulty or higher.
Development Timeline - Normal difficulty or higher.
Duke 3D Freeze Ray (freeze ray fires bouncing ice projectiles) - Normal difficulty or higher.
Duke Sound Board - Normal difficulty or higher.
Game Speed (adjust game speed) - Normal difficulty or higher.
Grayscale Mode (black and white graphics) - Normal difficulty or higher.
Head Scale (adjust head size of enemies and NPCs) - Easy difficulty or higher.
Infinite Ammo (cheat; self-explanatory) - Normal difficulty or higher.
Instagib (cheat; enemies killed with one shot and always gib) - Normal difficulty or higher.
Invincibility (cheat; no damage from bullets or explosions) - Normal difficulty or higher.
Mirror Mode (graphics are mirrored horizontally) - Normal difficulty or higher.
Movies - Normal difficulty or higher.
Screenshots - Normal difficulty or higher.
Triptych Office Photos - Normal difficulty or higher.
"Damn! It's Late...": Microwaved Rat
There is a room with a microwave. Directly under the microwave is a cupboard which can be opened to find a rat. You can pick up the rat and put it in the microwave. Note: This room is also shared with the Duke Nukem Fanboy.
Easy "Sticky Bomb Like You!" Achievement/Trophy
At the beginning of "The Duke Dome" chapter, you will get an unlimited amount of explosives when entering a building. Throw a trip mine directly on one of the enemies to earn the "Sticky Bomb Like You!" achievement or trophy.
Easy "Sunday, Black Sunday" Achievement/Trophy
In the "Duke Lives" chapter, at the very beginning of your first fight, you will see a blimp in the background. Keep shooting it until you earn the "Sunday, Black Sunday" achievement or trophy.
Easy "Turd Burglar" Achievement/Trophy
Poop can be found in toilets. There is some poop in the toilets in the room where the game begins, in the "Duke Lives" chapter. Grab poop from a toilet and throw it to earn the "Turd Burglar" achievement or trophy.
Christian Bale Reference
In the "Damn It's Late" mission, after walking off the set you will see an actor yelling at someone. He says things like "Do you want me to trash you're mics? DO YOU?" and "You're a nice guy, you really are but you're a fucking amateur". This is a reference to when Christian Bale freaked out on the set of Terminator Salvation.
Tommy Tutone Reference
In the bathroom in the Strip Club level, above one of the urinals there is some grafitti that reads "Jenny - 867-5309". This is a reference to the Tommy Tutone song of the same name.
Inception Reference
In the Strip Club level, enter the room where you can microwave the popcorn. Look on the desk where you can use the security camera and you will see a spinning top, like the one Leonardo DiCaprio uses in Inception.
Dead Space Reference
In "The Hive" chapter, after you tickle the first door, turn to your left and begin walking forward. You will have to crouch to get under the bridge. Once you do, you will see and dead EDF Soldier with Isaac Clarke's signature engineer helmet.
Mortal Kombat Reference
In the Duke Nukem soundboard, there is an entry called "Fatality". when you select it, Duke says "Duke wins, Fatality."
Unlock Weapon Clothing
Backwards Baseball Cap - Get 250 kills with the Shotgun (Burger Face III).
Baseball Cap - Get 75 kills with pipe bombs (Splatter king III).
Brain Sucker - Get 250 kills with the Enforcer (Laser Seeking Missiles III).
Canadian Flag Logo - Get 75 kills with the Garter Pistol (Tiny But Deadly III).
Cheese Hat - Get 250 kills with the Ripper (Swiss Cheese III).
Detonator Logo - Get 250 kills with the Rocket Launcher (Boom Goes the Weasel III).
Hoplite Helmet - Get 75 melee kills (Punchy McPuncher III).
I Shot Stupid Logo - Get 250 kills with the Railgun (Right In the Eye III).
Jester Hat - Get 75 kills with trip mines (Watch your step III).
Military Hat - Get 250 kills with the Pistol (Size Doesn't Matter III).
Retro Duke Logo - Get 250 kills with the Devestator (Meat Grinder III).
Ski Goggles - Execute a frozen player 75 times (Ice to See You III.)
Tie-Dye Shirt - Get 250 kills with the AT laser (Medium Rare III).
Uncle Sam Hat - Stomp on 75 enemies (Pee Wee Vermin III).
Wolf Logo - Get 75 kills with Steroids (Roid Rage III).
WTF Logo - Get 75 kills with exploding barrels (Smile You Son of a Bitch III).